OPTIMAL TIMING OF ESOPHAGEAL STENTING BY THE MODEL
OF CHEMICAL BURNS OF ESOPHAGUS IN THE EXPERIMENT 

Nikol'skiy Valeriy Isaakovich, Doctor of medical sciences, professor, sub-department of surgery, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), pmisurg@gmail.com
Klimashevich Aleksandr Vladimirovich, Candidate of medical sciences, associate professor, sub-department of surgery, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), klimashevich78@gmail.com
Fedorova Mariya Gennad'evna, Candidate of medical sciences, associate professor, sub-department of clinical morphology and forensic medicine with a course of oncology, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), fedorovamerry@gmail.com
Kupryushin Aleksey Stepanovich, Candidate of medical sciences, associate professor, head of sub-department of clinical morphology and forensic medicine with a course of oncology, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), kmismsko@mail.ru
Kupryushina Natal'ya Viktorovna, Candidate of medical sciences, head of morbid anatomy unit, Penza regional clinical hospital named after N. N. Burdenko (28 Lermontova street, Penza, Russia), kmismsko@mail.ru
Shabrov Aleksandr Valer'evich, Resident, sub-department of surgery, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), alexundead12@yandex.ru

617-89.844

Background. The article is aimed at determination of time period of recanalization of lumen in the treatment of post-burn strictures of esophagus.
Materials and methods. In 15 sexually mature rabbits of "Chinchilla" breed the authors modeled chemical burns of esophagus. The researchers evaluated morphological changes in the esophageal wall burn zone in dynamics.
Results. It is established that by the 30th day after the burn there occurs the relief of inflammatory processes and the connective tissues and epithelium are developing.
Conclusions. The optimal time of esophageal stenting according to histology is the terms from 14 to 21 days.

esophagus burn, stricture, experiment.

1. Dorzhiev B. D., Tykhenova M. L., Punsukov K. D. Byulleten' Vostochno-Sibirskogo nauchnogo tsentra Sibirskogo otdeleniya Ros. Akademii med. nauk [Bulletin of West-Siberian center of the Siberian branch of the Russian Academy of Medical Sciences]. 2012, no. 4 (86), part 2, pp. 193–197.
2. Luzhnikov E. L. Klinicheskaya toksikologiya [Clinical Toxicology]. Moscow: Med-itsina, 2008, pp. 189–213.
3. Bel'kova T. Yu. Sibirskiy meditsinskiy zhurnal [Siberian medical journal]. 2001, no. 4, pp. 13–17.
4. Luzhnikov E. A., Sukhodolova G. N. Ostrye otravleniya u vzroslykh i detey [Acute poisoning of adults and children]. Moscow: Eksmo, 2009, 560 p.
5. Klimashevich A. V., Nikol'skiy V. I., Bogonina O. V. Izvestiya vysshikh uchebnykh zavedeniy Povolzhskiy region. Meditsinskie nauki [University proceedings. Volga region. Medical sciences]. 2012, no. 1 (21), pp. 52–61.
6. Klimashevich A. V., Nikol'skiy V. I., Bogonina O. V., Shabrov A. V. Fundamental'nye issledovaniya [Fundamental research]. 2013, no. 2, part 1, pp. 83–87.
7. Pat. 134422 Russian Federation, A61B18/14. Ustroystvo dlya modelirovaniya lokal'nogo ozhoga pishchevoda u eksperimental'nykh zhivotnykh [Device for simulation of esophagus local burns in experimental animals]. V. I. Nikol'skiy, A. V. Klimashevich, A. V. Shabrov; Federal State Educational Institution of Higher Professional Education "Penza State University". № 2013123887/14, 24 march 2013.